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3.0
Jun 30, 2018
06/18
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Lucas Mäde; Sebastian Schmitz; Georg Rollmann; Hanno Gottschalk; Tilmann Beck
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A probabilistic risk assessment for low cycle fatigue (LCF) based on the so-called size effect has been applied on gas-turbine design in recent years. In contrast, notch support modeling for LCF which intends to consider the change in stress below the surface of critical LCF regions is known and applied for decades. Turbomachinery components often show sharp stress gradients and very localized critical regions for LCF crack initiations so that a life prediction should also consider notch and...
Topics: Numerical Analysis, Mathematics
Source: http://arxiv.org/abs/1702.05759
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52
Oct 25, 2014
10/14
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Mugasa, Joseph; Qi, Weihong; Rusch, Sebastian; Rottmann, Matthias; Beck, Hans-Peter
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This article is from Malaria Journal , volume 11 . Abstract Background: Severe malaria has been attributed to the expression of a restricted subset of the var multi-gene family, which encodes for Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 mediates cytoadherence and sequestration of infected erythrocytes into the post-capillary venules of vital organs such as the brain, lung or placenta. var genes are highly diverse and can be classified in three major groups (ups A, B...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488018
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52
Oct 23, 2014
10/14
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Wilding, Corina; Bell, Katharina; Beck, Sabine; Funke, Sebastian; Pfeiffer, Norbert; Grus, Franz H.
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This article is from PLoS ONE , volume 9 . Abstract The family of synuclein proteins (α, β and γ) are related to neurodegenerative disease e.g. Parkinson disease and Morbus Alzheimer. Additionally, a connection between γ-synuclein and glaucoma, a neurodegenerative disease characterized by a progressive loss of retinal ganglion cells, which finally leads to blindness, exists. The reason for the development of glaucoma is still unknown. Recent studies evaluating the participation of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940944
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6.0
Jun 30, 2018
06/18
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Frank Balle; Tilmann Beck; Dietmar Eifler; Jan Henrik Fitschen; Sebastian Schuff; Gabriele Steidl
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In this paper we deal with the important problem of estimating the local strain tensor from a sequence of micro-structural images realized during deformation tests of engineering materials. Since the strain tensor is defined via the Jacobian of the displacement field, we propose to compute the displacement field by a variational model which takes care of properties of the Jacobian of the displacement field. In particular we are interested in areas of high strain. The data term of our...
Topics: Numerical Analysis, Mathematics
Source: http://arxiv.org/abs/1704.06028
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140
Oct 13, 2014
10/14
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Dietz, Olivier; Rusch, Sebastian; Brand, Francoise; Mundwiler-Pachlatko, Esther; Gaida, Annette; Voss, Till; Beck, Hans-Peter
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This article is from PLoS ONE , volume 9 . Abstract Survival and virulence of the human malaria parasite Plasmodium falciparum during the blood stage of infection critically depend on extensive host cell refurbishments mediated through export of numerous parasite proteins into the host cell. The parasite-derived membranous structures called Maurer's clefts (MC) play an important role in protein trafficking from the parasite to the red blood cell membrane. However, their specific function has...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111544
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5.0
Jun 30, 2018
06/18
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Miklos Vincze; Sebastian Borchert; Ulrich Achatz; Thomas von Larcher; Martin Baumann; Claudia Hertel; Sebastian Remmler; Teresa Beck; Kiril Alexandrov; Christoph Egbers; Jochen Froehlich; Vincent Heuveline; Stefan Hickel; Uwe Harlander
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The differentially heated rotating annulus is a widely studied tabletop-size laboratory model of the general mid-latitude atmospheric circulation. The two most relevant factors of cyclogenesis, namely rotation and meridional temperature gradient are quite well captured in this simple arrangement. The radial temperature difference in the cylindrical tank and its rotation rate can be set so that the isothermal surfaces in the bulk tilt, leading to the formation of baroclinic waves. The signatures...
Topics: Fluid Dynamics, Physics
Source: http://arxiv.org/abs/1403.2715
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4.0
Jun 29, 2018
06/18
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Michael Sendner; Pabitra K. Nayak; David A. Egger; Sebastian Beck; Christian Müller; Bernd Epding; Wolfgang Kowalsky; Leeor Kronik; Henry J. Snaith; Annemarie Pucci; Robert Lovrinčić
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Lead-halide perovskites are promising materials for opto-electronic applications. Recent reports indicated that their mechanical and electronic properties are strongly affected by the lattice vibrations. Herein we report far-infrared spectroscopy measurements of CH$_{3}$NH$_{3}$Pb(I/Br/Cl)$_{3}$ thin films and single crystals at room temperature and a detailed quantitative analysis of the spectra. We find strong broadening and anharmonicity of the lattice vibrations for all three halide...
Topics: Materials Science, Condensed Matter
Source: http://arxiv.org/abs/1607.08541
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75
Oct 5, 2014
10/14
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Downey, Laura E; Fletcher, Phillip D; Golden, Hannah L; Mahoney, Colin J; Agustus, Jennifer L; Schott, Jonathan M; Rohrer, Jonathan D; Beck, Jonathan; Mead, Simon; Rossor, Martin N; Crutch, Sebastian J; Warren, Jason D
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This article is from Journal of Neurology, Neurosurgery, and Psychiatry , volume 85 . Abstract Background: Mutations in C9ORF72 are an important cause of frontotemporal dementia (FTD) and motor neuron disease. Accumulating evidence suggests that FTD associated with C9ORF72 mutations (C9ORF72-FTD) is distinguished clinically by early prominent neuropsychiatric features that might collectively reflect deranged body schema processing. However, the pathophysiology of C9ORF72-FTD has not been...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145454
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93
Oct 18, 2014
10/14
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Tsai, Vicky Wang-Wei; Manandhar, Rakesh; J?rgensen, Sebastian Beck; Lee-Ng, Ka Ki Michelle; Zhang, Hong Ping; Marquis, Christopher Peter; Jiang, Lele; Husaini, Yasmin; Lin, Shu; Sainsbury, Amanda; Sawchenko, Paul E.; Brown, David A.; Breit, Samuel N.
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This article is from PLoS ONE , volume 9 . Abstract Macrophage inhibitory cytokine-1 (MIC-1/GDF15) modulates food intake and body weight under physiological and pathological conditions by acting on the hypothalamus and brainstem. When overexpressed in disease, such as in advanced cancer, elevated serum MIC-1/GDF15 levels lead to an anorexia/cachexia syndrome. To gain a better understanding of its actions in the brainstem we studied MIC-1/GDF15 induced neuronal activation identified by induction...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074070
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Oct 25, 2014
10/14
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Jorgensen, Sebastian Beck; O'Neill, Hayley M.; Sylow, Lykke; Honeyman, Jane; Hewitt, Kimberly A.; Palanivel, Rengasamy; Fullerton, Morgan D.; Oberg, Lisa; Balendran, Anudharan; Galic, Sandra; van der Poel, Chris; Trounce, Ian A.; Lynch, Gordon S.; Schertzer, Jonathan D.; Steinberg, Gregory R.
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This article is from Diabetes , volume 62 . Abstract Obesity is associated with chronic low-grade inflammation that contributes to defects in energy metabolism and insulin resistance. Suppressor of cytokine signaling (SOCS)-3 expression is increased in skeletal muscle of obese humans. SOCS3 inhibits leptin signaling in the hypothalamus and insulin signal transduction in adipose tissue and the liver. Skeletal muscle is an important tissue for controlling energy expenditure and whole-body insulin...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526029
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254
Aug 21, 2020
08/20
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Mark Lander, Adam Southgate, Pamela Johnson, Dodgy Roger, Veronica Hodges, Asao Shimura, Parisa Damandan, Ali Pezeshk, Valeriya Kirienko, Orna Hatzor, Ion Georgescu, Lisa Christensen, Matthias Schwethelm, Carole Penin, Judith Chestnutt, Judith Staines, Jorge Valente, Eleanora Franco, Susan Thomas, Linda McCausland, Solveiga Ploskonka, Sebastian Pastor Ploskonka, Christine Higgins, Sheryl Jaffe, Gayle Fitzpatrick, Suzi Ballenger, Donna Beck, Donna Lilborn, Stephanie Damoff, Claude Aimée...
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The International Handmade Paper Swatch Swap Yearbook is the result of makers-to-makers sharing of 2x3 inch swatches of handmade paper. Includes classic fibers, experimental, art, recipes, advice, resources... This is the 20th edition from 2019, edited by Yama Ploskonka, of Papel Texano in Austin, Texas
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Topics: papermaking, handmade paper, community, paper samples, paper art, 2019
